Human Papilloma Virus (HPV) infection is the primary cause of virtually all cervical cancers. Cervical cancer despite being largely preventable is still the leading cause of gynaecological cancer related death among females in developing countries. This study was carried out to molecularly characterized Human Papilloma Virus among women attending selected hospitals in Sokoto, Sokoto State, Nigeria. This study involves the analysis of high vaginal swab obtained from 208 women. The high vaginal swab samples were analysed using PCR, DNA sequencing and phylogenetic analysis of the identified genotypes. Only two Human papilloma virus genotypes (HPV type 18 and 58) were detected in this study with Human papilloma virus type 58 as the most prevalent. This study identified only two Human papilloma virus genotypes (HPV types 18 and 58) in Sokoto, Nigeria which can serve as basis for establishing vaccine in the study area.

Introduction and Aim: Nuchal-type fibroma (NTF) is a rare benign fibrous proliferation primarily originating from the dorsocervical neck region. Enzinger and Weiss first characterized it in 1988, highlighting its distinct histopathological features. Description of the Case Report: We present a case of 71-year-old South Asian male patient with painless swelling over the nape of neck, highlighting the challenges in diagnosis of NTF. Clinical examination, imaging, and cytological findings initially suggested a lipomatous lesion. Histopathological evaluation revealed characteristic features consistent with NTF, emphasizing the importance of histopathological assessment for accurate diagnosis. Despite its benign nature, vigilance is essential due to the potential for recurrence. Conclusion: This case underscores the need for a comprehensive understanding of NTF's clinical and histopathological features to facilitate optimal management and improve patient outcomes.

Mycetoma is a chronic, granulomatous subcutaneous infection characterized by a triad of inflammation, painless tumour-like lesions and multiple sinuses discharging grains [1]. In Mexico, 97% of mycetomas are caused by bacteria of the order Actinomycetales, where Nocardia brasiliensis is the most important agent, while in eumycetomas the most important genera are Madurella spp. and Trematosphaeria spp [4]. This pathology is more common in men (3:1 to 5:1) between the age of 20 and 40 years, and up to 75% of patients present the injury (being the entry way) in the lower extremity, most commonly in the foot (70%). Other sites include the head, neck, chest, shoulders and arms [6, 7]. The diagnosis of mycetoma is based on clinical presentation, imaging studies and identification of the causative organisms in relevant clinical samples taken from affected tissues using fine-needle aspiration, or surgical biopsy. The diagnosis of mycetoma is based on clinical presentation, imaging studies and identification of the causative organisms in relevant clinical samples taken from affected tissues using fine-needle aspiration, or surgical biopsy. Imaging including X-ray, ultrasound, MRI and CT scan examinations may be required to characterize the spread and extent of disease [3].

Ocular infections are a growing global health concern, affecting millions worldwide. This review explores the bacterial profile of various ocular infections to aid in developing effective treatments and preventive strategies. The eye's complex anatomy, including the cornea, pupil, iris, lens, and retina, makes it susceptible to infections that can lead to vision loss. Bacteria are a leading cause of these infections, with common culprits including Escherichia coli, Streptococcus, Neisseria gonorrhoeae, and Staphylococcus aureus. Environmental factors, allergies, and poor hygiene can exacerbate the risk. Treatment options range from antibiotics and antivirals to eye drops and surgery. Understanding the bacterial profile of ocular infections is crucial for targeted interventions and improved public health outcomes.

Introduction: The high cost and limited availability of traditional feeds at certain times of the year is one of the biggest constraints to animal production. This study aimed to demonstrate the effect of using dried date peels, and baker's yeast (Saccharomyces cerevisiae, S.s) in different incubation periods on rumen fermentations. Three levels of dried date peels (15%, 30%, and 60%), with different baker's yeast (Saccharomyces cerevisiae, S.C.) are used in this study in vitro condition. Results: The different treatments used in this study had a significant increase in ruminant gas production. Conclusion: Baker's yeast (Saccharomyces cerevisiae, S.C.) and date peels do not affect reducing rumen gas, indeed, these treatments increase the gas produced by the feed in vitro conditions.

Next-generation sequencing (NGS) has reformed infectious disease management, including COVID-19. While real-time polymerase chain reaction (PCR) is widely used for rapid pathogen detection, it requires predefined targets. NGS offers an unbiased approach, detecting multiple pathogens simultaneously without prior knowledge. Despite its potential, NGS implementation in clinical settings faces challenges like high costs and technical complexity. NGS platforms like Illumina, Ion Torrent, and Nanopore provide high-throughput sequencing, identifying pathogens and resistance markers. Applications include whole genome sequencing (WGS), metagenomic NGS (mNGS), and targeted NGS (tNGS). Integrating NGS with conventional methods could improve diagnostics, but current evidence is mixed for supporting its widespread clinical use.

This study aimed to characterize Escherichia coli (E. coli) isolates from urinary tract infections (UTIs) in Iraq and compare them with international strains. Twenty midstream urine samples from UTI patients were cultured on MacConkey and nutrient agar plates. All bacterial isolates were identified using Vitek 2 system, followed by DNA extraction with the Goya Gene kit. Specific primers were used to detect E. coli, and positive samples were sequenced using the Sanger method. Phylogenetic analysis was conducted to elucidate the genetic relationships among the isolates. The results revealed a high similarity between local Iraqi E. coli isolates and national strains, with minor differences. The phylogenetic tree analysis identified three distinct strains, with an 81% similarity among most isolates, though one international strain was notably distant. The study highlights on rising the frequency of UTIs and the monetary problems they impose on both the governments and patients, emphasizing the need for active drugs that can be rapidly implemented in medical settings. This research underscores the importance of understanding local bacterial populations to inform treatment strategies, as UTIs commonly result from bacterial resistance to existing treatments. UPEC frequently targets the urethra, bladder, and kidneys, initiating infections through colonization and subsequent invasion of the bladder epithelium.