Adults often complain of back and sciatic discomfort. People and the country suffer huge financial losses as a result of shorter working hours. Before treating these patients, a thorough examination is required. A lack of medical or surgical treatment may aggravate symptoms. The goal of this study is to determine if acupuncture has any impact on the symptoms of PLID. This inquiry took place at Suo-Xi Hospital, Shaan Tower, Chamelibagh, Santinagar, Dhaka, Bangladesh. A 43-year-old female patient has been experiencing low back discomfort that radiates down her left leg for the last four months. The diagnosis was confirmed with an MRI of the cervical spine. The follow-up research yielded good findings. After suffering from lower back discomfort for the previous five months, the patient felt much better on the second day of acupuncture and the reduced low back pain was no longer existent. Patients with PLID may benefit from acupuncture, according to this research.

Zinc(Ⅱ) induced neurological COVID-19 anti-thrombus formation has been established by that zinc induced inhibitive bronchial thrombosis and modulatory pulmonary thromboembolism are attained, causing COVID-19 activated anti-thrombus activity and leading to COVID-19 anti-thrombus formation. Zinc supplementation affected bronchial mucosal epithelial integrity, both under normal and zinc deficient conditions that there was an interaction between the individual zinc status. The other, zinc ions inhibit COVID-19 lung inflammation and promote platelet activation function that inhibits pulmonary thromboembolism, in which platelets could respond to changes in extracellular and intracellular Zn2+ concentration. Zinc-induced platelet aggregation, low concentrations of ZnSO4 and zinc chelation involve platelet activation and potentiated platelet aggregation, in which Zn2+ plays a major role in the regulation of coagulation that zinc inhibit blood coagulation against COVID-19 infection. Zn2+ can modulate platelet and coagulation activation pathways, including fibrin formation that the release of ionic Zn2+ store contributes to the procoagulant role of Zn2+ in platelet-dependent fibrin formation. Further, zinc may reduce neurological resultings in COVID-19 patients that Zn2+ promotes inflammatory cytokine as a neurodegenerative disorder and the coronaviruses can affect the nervous system through blood circulation, causing neuro-inflammation. Zinc ions can inhibit inflammation, platelet behaviour function, and blood coagulation. Hence, zinc ions promote neurological anti-thrombosis formation during ROS production and excessive oxidative stress against COVID-19 infection. Persistent zinc intake for severe aggravation of COVID-19 has been suggested to be 8–11 mg/day for adults (upper intake level 40 mg/day) and suggesting that a zinc intake of 30–70 mg/day might aid in the RNA virus control. Accordingly, Zn2+ ions-binding molecular mechanism has been clarified that Zn2+ ions may be bound with COVID-19 inflammatory, platelet, coagulation, and thrombus various proteins by Zn2+ ions-centered tetrahedrally binding protein molecular coordination pattern.

Biosafety, understood as a protocol to avoid contagion, illness and death of people, has established itself as a central topic for discussion on the public agenda. The objective of the present work was to explore the perceptual dimension of biosafety. A retrospective, exploratory and documentary work was carried out with a selection of sources indexed to regional repositories. The prevalence of the informative and speculative dimension of biosecurity was established, suggesting to extend the project to other risk scenarios.

Background: Hydrocephalus is a condition in which excess fluid accumulates in the brain resulting in dilatation of the ventricles. The prognosis of hydrocephalus depends on the cause and severity of the condition. Computed tomography (CT) is one of the imaging modalities used for diagnosis and evaluation of treatment options as well as for follow up and monitoring of the patients. Aim and Objectives: This study is aimed at documenting CT findings of hydrocephalus in children at Usmanu Danfodiyo University Teaching Hospital (UDUTH) Sokoto with specific objectives of determining the common causes of hydrocephalus and comparing the incidence of congenital and acquired hydrocephalus. Materials and Methods: This was a four-year retrospective study of 100 consecutive children with clinical and/or Computarized Tomographic (CT) diagnosis of hydrocephalus who had CT scan at the Radiology Department of UDUTH Sokoto, North Western Nigeria. Data and the images were retrieved from the departmental archives and patient’s case folders. These data regarding the demographics of patients, clinical history and examination, cranial CT findings and radiological measurements were entered into the proforma. Data was analyzed using SPSS statistical software package version 20. Results: The age range of patients was from 5 days to 14 years with male/female ratio of 1.6:1. Congenital hydrocephalus accounted for 54% while acquired hydrocephalus occured in 46%. Non communicating hydrocephalus was the predominant form of hydrocephalus accounting for 59% while communicating hydrocephalus occured in 41% of patients. Aqueductal stenosis (32%) was the commonest cause of hydrocephalus followed by post meningitic hydrocephalus (22%) and intracranial tumours (16%) respectively. Conclusion: This study shows that congenital hydrocephalus is the predominant type in the study population. Aqueductal stenosis was the commonest cause of hydrocephalus.

Abstract: COVID-19 has been declared a global pandemic by the World Health Organization and is responsible for hundreds of thousands of deaths worldwide. COVID-19 is caused by SARS-CoV-2, and common clinical symptoms include fever, cough, sore throat, headache, and fatigue. The cardiovascular system is affected in this infection, with complications including myocardial injury, myocarditis, acute myocardial infarction, heart failure, dysrhythmias, and venous thromboembolic events. Current therapies for COVID-19 may interact with cardiovascular medications. Myocardial injury is relatively common in patients with COVID-19, accounting for 7%-23% of cases, and is associated with a higher rate of morbidity and mortality [1]. In patients with COVID infection clinical suspicion is necessary to diagnose myocarditis as an important complication of this infection. Here we present a patient who developed shortness of breath and orthopnea following sore throat and myalgia and was eventually treated with a diagnosis of myocarditis and discharged from the hospital in relatively good general condition.

Abstract: Described as the most common cause of gastric outlet obstruction and the most common surgical cause of vomiting in infants, Hypertrophic Pyloric Stenosis (HPS) is defined as a hyperplasia of smooth muscle fibers of the pylorus that is responsible for the narrowing of the pyloric canal and obstruction of gastric emptying. It occurs at a rate of 1–4 per 1000 live births with a male to female ratio 4:1. The classic presentation of HPS is nonbilious, projectile vomiting in a full-term neonate with a classic presentation at 3 to 4 weeks of age. We report in here a delayed presentation of HPS in an infant aged 4 months who presented with projectile nonbilious recurrent episodes of post prandial vomiting, where history, examination and investigations supported the diagnosis of HPS and Ramstedt's pyloromyotomy was curative.

Abstract: Large wounds with heavy exudate are known to cause moisture related skin damages that can be distressing to the patient especially when he has pain that disturbs his sleep and other activities. Honey, known to be used to treat wound in ancient era, has antimicrobial properties, is anti- inflammatory and is known to promote wound healing. This case report demonstrates the efficacy of Indian medical grade honey in high exuding wound with peri wound skin damage.