To psychologists, inspiration is a very strong and rapid surge of creativity which pushes a person into original ideas or insights. The study reported in this article was undertaken by Patanjali Yoga Research Centre, Kozhikode, Kerala State, India among a randomly selected sample of 100 yoga practitioners from Kerala State using a questionnaire containing the measure of feeling of inspiration in life, how far yoga practice has contributed to feeling inspired in life, and the characteristics of the yoga practitioners, namely, sex, age, marital status, period of yoga practice (in months), and the effects obtained through yoga practice. Equal interval Likert scale scoring was adopted for the responses to feeling irritated and all the characteristics of the respondents except age, for which the numerical value of the age was considered for analysis. The total inspiration score and the total score for contribution of yoga practice to feeling inspired in life were worked out as the sum of the item scores. The data was analysed as proportion reporting, as scores and through statistical tests. The results show that 60 % of the respondents have total inspiration score in the range of 71.4 to 100 % of the maximum possible score. This is supported by the responses of the yoga practitioners on the level and frequency of experience of various items related to inspiration considered in the study. Statistical significance exists in the difference in total inspiration score based on period of yoga practice. The lowest score is obtained by people who have done yoga for a period of up to 1 year, followed by a comparatively higher score in the case of people having 3 to 4 months of yoga practice and the highest score for those who have practiced yoga for more than 12 months. Statistical significance is observed in the difference in total inspiration score based on the age of the yoga practitioners. Comparatively younger respondents get a higher score than those in the higher age groups. Statistical significance of the difference in total inspiration score of the respondents based on marital status of the yoga practitioners is also evident. Unmarried respondents get a comparatively higher score than those who are married. The results of regression analysis of the characteristics of the respondents on total inspiration score shows that marital status, period of yoga practice, sex, and the effects obtained through yoga practice by the respondents contribute to 62 % of the variation observed in their total inspiration score. Among them, the regression coefficient is significant in the case of the characteristic, namely, the effects obtained through yoga practice. 85 % of the yoga practitioners report 62.5 to 100 % contribution of yoga practice to feeling inspired in life. Feeling inspired in life would help to boost motivation, promote positive coping strategies and foster a sense of purpose, thus improving the psychological wellbeing of the yoga practitioners This could prove useful in reducing their psychological and psychiatric problems also.

Background: Syringomyelia (Syr) is a rare, progressive neurological disorder characterized by the formation of a fluid-filled cavity (syrinx) within the spinal cord, leading to sensory and motor dysfunction. It is challenging to cure, and available treatments often have limited effectiveness. Recurrence is commonly observed after treatment. Objective: This study explores the role of Guan Yin Citta Dharma Door in managing Syr, presenting 2 cases in which Dharma practice led to significant symptom relief. Methods: This study examines two cases of patients diagnosed with Syr who adopted Buddhist practices based on the teachings of Dharma Master Jun Hong Lu. The first patient practiced making vows, reciting Buddhist scriptures, and liberating lives, with progress assessed through symptom relief and overall well-being. In the second case, the patient incorporated Dharma practices to aid recovery following surgery. Results: Through dedicated Dharma practice, the patient in Case 1 experienced significant symptom improvement, reduced pain, and survival beyond the medically expected prognosis. Similarly, in Case 2, Buddhist practices not only supported post-surgical recovery but also alleviated persistent pain and emotional suffering, leading to a profound transformation. These cases underscore the potential benefits of spiritual healing in managing Syr. Conclusion: This study suggests that Guan Yin Citta Dharma Door may provide an alternative approach to improving the quality of life in patients with Syr. While further research is needed, the integration of Dharma practices with conventional treatments may offer a more holistic strategy for managing neurological diseases.

Infectious mononucleosis (IM) or Mononucleosis syndrome is caused by an acute infection of Epstein-Barr virus (EBV). This study was aimed at determining the levels of haemoglobin, total white blood cell (TWBC) count, neutrophils, lymphocytes, monocytes and eosinophils in patients infected with infectious mononucleosis at Federal Teaching Hospital, Owerri. A total of sixty subjects (30 patients and 30 controls) were enrolled in the study after giving their informed consent and completing questionnaires. The procedure was carried out at Federal Teaching Hospital, Owerri. Five millilitres of venous blood sample was collected at the ante-cubital vein aseptically and was dispensed into ethylenediaminetetraacetic acid (EDTA) containers. The EDTA containers were properly labeled with the subject’s name, sample number and date of collection. Haemoglobin was determined using the cyanmethaemoglobin method, TWBC was determined using the improved Neubauer counting chamber, while the differential count was determined using Romanowsky staining method. Data generated were analyzed using SPSS version 27, and mean, standard deviation, t-test, correlation and p-value were determined. The mean values of haemoglobin (8.9±1.44)g/dl and neutrophils (28.53±12.77)%, were significantly reduced in patients with infectious mononucleosis when compared to the controls (12.83±1.34)g/dl and (54.27±10.20 ((p=0.000 and p=0.001)) The mean values of TWBC (17.66±8.54)%, lymphocytes (59.87±13.14)% and monocytes (10.30±6.68)%)% were significantly increased in patients with infectious mononucleosis when compared to the controls (6.17±2.53)%, (49.23±13.57)% and (5.93±2.91)% ) respectively (p=0.000, p=0.003 and p=0.002). There was no significant difference in the mean value of eosinophil count in infectious mononucleosis (1.30±1.56)% (p=0.784) when compared to the controls (1.20±1.24)%. There were no significant differences in the mean values of haemoglobin, TWBC, neutrophil, lymphocyte, monocyte and eosinophil counts in male patients with infectious mononucleosis (9.14±1.52)g/dl, (19.16±9.36)x109/L, (27.69±11.18)%, (59.44±11.17), (10.13±6.12)% and (1.44±1.89)% when compared to the female patients (8.82±1.38)g/dl, (15.94±7.46)x109/L, (29.50±14.38)%, (60.36±15.51)%, (10.50±7.50)% and (1.14±1.09)% (p=0.568, p=0.311, p=0.705, p=0.852, p=0.881 and p=0.614). There was a non-significant positive correlation of haemoglobin with TWBC, neutrophils, lymphocytes, monocytes and eosinophils in infectious mononucleosis patients (r=0.17, p=0.357; r=0.15, p=0.421, r=0.07, p=0.730, r=0.11, p=0.563 and r=0.06, p=0.751). In conclusion, the data in the present study showed that infectious mononucleosis is characterized by increase in lymphocytes and monocytes with decreased levels of haemoglobin and neutrophils. Haemoglobin concentration does not have any relationship with white blood cells in patients with infectious mononucleosis. In the management and treatment of patients with infectious mononucleosis, complete blood count should be incorporated as a routine test, so as to aid in the diagnosis.

Today human mankind stands in the middle of deep scientific understanding of United Nations and Global Sustainable Development Goals. In the similar vision, medical science and health science perspectives are in the middle of scientific rejuvenation and scientific steadfastness. Schizophrenia is an extremely difficult ailment to treat. The author is suffering from schizophrenia since November,1993. He is diagnosed with glaucoma in his right eye since October, 2012. Today he is beset and replete with different symptoms of schizophrenia. Long years of illness has passed since 1993. Science and technology today has no answers towards the cure and treatment of schizophrenia. The author in this article elucidates with cogent and lucid insight his medical diagnosis of the treatment of schizophrenia and the immense trials and tribulations in his life. With immense agony and pain, the author depicts profoundly the needs of psychological and psychiatric help in the treatment and cure of schizophrenia.

The various demands that are placed on students by both internal and external sources have resulted in stress in their academic lives. Teenagers are particularly vulnerable to the problems associated with academic stress because they are adapting to both personal and cultural changes. Thus, it is crucial to comprehend the origins and consequences of academic stress to create efficient intervention strategies. The study's quantitative research approach included the use of the Academic [5]. Stress Scale to identify participants from four streams: commerce, management, humanities, and basic sciences. Five features of sources were further examined: insufficient study facilities, teacher-student connections, interpersonal difficulties with teachers, fear of failure, and personal inadequacy. Additionally, gender differences were found. School psychologists and counselors could create more effective counseling modules and intervention tactics to help pupils cope with stress if they had a better understanding of the causes of stress [6].

Background and objective: The study of the S1P signaling pathway in the context of diabetes offers a novel perspective for understanding the mechanisms underlying cognitive decline and developing new therapeutic strategies. Material and methods: The study involved 24 Wistar rats, divided into three groups: group 1 was given distilled water and served as a control group; group 2 was made up of rats made diabetic and given distilled water; group 3 was made up of rats made diabetic and treated with D-erythro-dihydrosphingosine (SPK1 and SPK2 inhibitor). Behavioral tests included object recognition and maze tests, and Rt-PCR was used to assess sphingosine-1-phosphate expression. Results: The study revealed significant differences in weight between rats, with a notable decrease observed from day 7 onwards. It also revealed significant differences in the time spent exploring objects and the mental influence of diabetes on the acquisition of spatial knowledge. The study also revealed that diabetes affects working memory and inhibits S1P expression in the hippocampal region. Conclusion: The study reveals significant differences in exploratory behavior and memory capacity between diabetic and normal rats, highlighting the negative effects of diabetes on memory.

Medical education is highly demanding, with students facing intense academic, emotional, and professional challenges. First-year students face the pressures of adjusting to a rigorous curriculum and new social environments, while final-year students experience heightened stress related to career uncertainty and impending clinical responsibilities. Understanding the sources of stress and coping strategies at different stages of training is crucial for developing targeted interventions that promote student well-being and academic success. Hence, this study aimed to assess the differences in perceived stress sources and coping strategies among first and final-year undergraduate medical students using an online survey. Sociodemographic information was collected, and stress levels were measured using the Perceived Stress Scale, while sources of stress were identified with the Medical Student Stressor Questionnaire. Coping strategies were evaluated using the Brief-COPE. Statistical analysis was performed using SPSS, with Chi-square tests to compare groups. A total of 264 medical students (132 first-year, 132 final-year) participated in the study. First-year students reported higher levels of stress, with 84.8% experiencing moderate stress, while final-year students showed more balanced stress distribution. Academic, interpersonal, and teaching-related stressors were most significant. First-year students predominantly used problem-focused coping, whereas final-year students employed more emotion-focused and avoidant coping strategies, with significant differences observed between the cohorts. Our results highlight the evolving stress experiences and coping strategies across the medical curriculum, underscoring the need for targeted mental health support that promote student well-being.