Today is the world of scientific and technological innovations in the field of medical science. Schizophrenia is a difficult ailment to treat. The author is suffering from schizophrenia for the last 30 years. Today since 2012 he is suffering from eye ailment and has glaucoma in his both eyes. The author lucidly and with cogent insight describes the agony and pain he experienced in the last 30 years. Today is the world of Fifth Industrial Revolution and application of United Nations Sustainable Development Goals. The vast world of the science of schizophrenia ailment needs to be re- envisioned and reframed as regards treatment and cure. Human sufferings and travails, trials and tribulations are immense for a mental patient suffering with this irrecoverable and monstrous ailment. Surely a new dawn in human civilization, man and mankind will emerge if doctors and medical health professionals takes active and positive steps in scientific research endeavor in the field of schizophrenia. The author deeply discusses these issues in this article. Science has advanced a lot since 1993 when the author was diagnosed with schizophrenia. The author deeply contemplates the need of psychology and psychiatry in the path towards a patient’s illness, treatment and revival.

Prevention of cognitive disorders and dementia is a major public health issue. Several studies have found a significant association between the existence of arterial hypertension and the onset of cognitive disorders and dementia (vascular or Alzheimer's disease) several years later. Arterial hypertension causes vascular changes that affect blood flow and brain metabolism. Cognitive disorders may be related to the presence of focal ischemic lesions (infarction, lacunae) and/or chronic white matter ischemia (leucoaraiosis) related to damage to the small cerebral arteries (arteriosclerosis). Recent work also suggests that cerebral hypoxia and endothelial function abnormalities lead to changes in the blood-brain barrier leading to an accumulation of β-amyloid protein in the brain and the formation of responsible amyloid plaques. of Alzheimer's disease. Few therapeutic trials have included cognitive assessment and/or diagnosis of dementia. They all raise some important criticisms: cognition is never the primary endpoint, follow-up is too short to study dementia; the evaluation of cognitive functions is very summary, the number of patients "lost to sight" is significant and the subjects at risk of developing dementia are in very low proportion.

Background: Chronic Obstructive Pulmonary Disease (COPD) is a chronic inflammatory disease due to smoking. It is avertable as well as treatable. COPD is a one of the main cause of morbidity and mortality affecting developed and developing countries. We aim to estimate burden of anemia at a tertiary care public sector hospital. Methods: This is a descriptive cross sectional study, done at JPMC Karachi in 2014. All COPD patients admitted in medicine and pulmonology departments were enrolled in this study. After informed consent, data of complete blood count was accessed from medical record and anemia was labeled as per operational definition. Data analyzed by SPSS version 16.0. Frequency and percentage proportion of qualitative variables, mean and standard deviation of numerical values were calculated with P value <0.05 was taken as significant. Results: Of 137 cases, 118(86.13%) were males and 19(13.87%) were females while male to female ratio was 6.2: 1. The average age and weight of the patients was 58.31±12.17 years and 59.36±10.56kg, similarly average duration of disease and hemoglobin of the patients was 5.69±4.42 years and 12.34±1.58 mg/dl respectively. 37.96% (52/137) patients were anemic in our study. Rate of anemia in COPD patients was not significant among age groups (p=0.076) and with duration of disease (p=0.22). Conclusion: Anemia seems to be a common feature in COPD (37.96%), mechanisms involved in the genesis of anemia in COPD are poorly studied. Low hemoglobin level can have adverse effects on certain respiratory parameters in COPD, increasing morbidity and mortality.

Attention Deficit Hyperactivity Disorder (ADHD) is not exclusively limited to childhood and adolescence, but it often persists in adults, where its prevalence in the general population is estimated at around 4% to 5%. It is accompanied by significant psychological, social and professionals. It is essential to ensure the detection of this disorder in adults. Indeed, psychostimulants have demonstrated therapeutic efficacy by numerous controlled studies. ADHD treatment should have the primary objective of improving attentional abilities and reducing impulsive behavior.

Vascular dementia corresponding to intellectual degradation significant enough to disrupt daily life, attributed to cerebral lesions of vascular origin. They are the second cause of dementia after Alzheimer's disease in the defeated countries. Their diagnosis is made difficult, on the one hand by the diversity of lesions potentially responsible for cognitive disorders and on the other hand by their frequent association with Alzheimer's disease. No treatment, other than preventive treatment, has been validated in vascular dementia. Several concepts have attempted or are attempting to characterize vascular dementias ("multiple infarct dementias", "vascular cognitive impairment", "vascular cognitive impairment").

Objectives: To study the aetiology of patients of delirium in old age, to study the severity of delirium in old age and to study the quality of life of family caregivers of delirium patients. Design: Prospective, observational, and cross sectional. Setting: Inpatient tertiary care hospital setting. Participants: Subjects with the diagnosis of Delirium qualifying according to ICD-10 (international classification of disease-10) and confirmed with CAM scale aged >60 years and Patient or patient’s family members willing to give consent. Measurements: Socio-demographic questionnaire, Confusion assessment method, Delirium index, Delirium aetiology check list, ICD -10 DCR, WHO QOL BREF and the Barthel index. Results: There is no significant association between delirium severity and WHOQoL. There is no significant association between Barthel index and WHOQoL. There is no significant association between WHOQoL and delirium aetiologies. There is no significant association between gender and WHOQoL. There is no significant association between marital status and WHOQoL. There is no significant association between religion and WHOQoL. There is no significant association between WHOQol and education. There is significant association between WHOQoL and occupation. Emloyed subjects have better quality of life than unemployed. There is no significant association between WHO QoL and residence. There is no significant association between WHOQoL and duration of delirium. There is no significant association between WHOQoL and medical comorbidities. There is no significant association between WHOQoL and substance use. There is no significant association between medical comorbidities and delirium aetiology. There is significant association between delirium severity and duration of delirium. As duration of delirium increases severity of delirium increases. There is no significant association between duration of delirium and delirium aetiology. There is no significant association between delirium severity and medical comorbidities. Conclusions: In this study results showed that there is significant association between delirium is an acute illness with sudden onset with maximum percentage of duration 2-4 weeks, delirium is more in males than females, majority of the care givers are spouses and parents, multiple aetiologies, diminished psychological QoL are associated with increased care giver burden. Family history of delirium is associated with better care giver burden. Employed subjects with delirium have better overall QoL. As duration of delirium increases, delirium severity increases.

Horseracing is among the foremost prevalent and increasingly lucrative industry sports within the country. The normal move must control a pure blood horse 10 times their weight which will act capriciously whether at rest or full gallop resulting in falls, kicks, or indeed gnawing wounds. In spite of the risks, jockeys don't have got to to the same quality of therapeutic care that's standard in essentially productive sports organizations. Past the mental and physical requests of preparing and execution persevered by any proficient competitor, racers are stood up to with wellbeing challenges interesting to their wear. In this audit of the writing, we point to teach sports medicine physicians with respect to the basic causes of wounds, depict damage administration, and make suggestions for fitting preventive strategies. By and large, there's a void of writing, and so our creators offer master supposition and empower others to urge included in making this a more secure don. Central to the vision of moved forward move pharmaceutical in Indonesia is the instruction of sports pharmaceutical specialists to get ready them for the specific care needs of their competitor patients. Past the mental and physical requests of preparing and execution persevered by any proficient competitor, racers are gone up against with wellbeing challenges interesting to their wear. The weight restricted-nature of horseracing [3] is an included challenge especially without relinquishing quality, and the instruments of harm regularly include a more noteworthy degree of force. In this survey of the writing, we point to teach sports pharmaceutical doctors with respect to the basic causes of wounds, portray damage administration, and make proposals for suitable preventive methodologies.