Syzygium cumini and Achras zapota leaves were easily available and commonly used in our day –to-day life. The present study aimed at the in-vitro comparative study of anthelmintic activity of aqueous extracts of leaves of Syzygium cumini, Achras zapota and mixed. The fruits were extracted separately with distilled water by maceration method .The various concentrations of the extract (50,100, 200mg/ml) respectively were screened for their anthelmintic activity using Pheritima posthuma. The activity was comparable with the standard drug albendazole. When the concentrations of the extract are increased, a gradual increase in anthelmintic activity is observed. The study involved the determination of time of paralysis (P) and time of death (D) of the worms. Aqueous extract of Syzygium cumini, Achras zapota and mixed showed anthelmintic activity but mixed extract was more efficient anthelmintic activity against Indian earthworms. The data were found statistically significant by using one way ANOVA (P< 0.0001).

Millions of patients present annually with chest pain, but only 10% to 15% have myocardial infarction. Lack of diagnostic sensitivity and specificity of clinical and conventional markers prevents or delays treatment and leads to unnecessary costly admissions. Comparative data are lacking on the new markers, yet using all of them is inappropriate and expensive. The older markers like aspartate amino-transferase, creatine kinase, lactate dehydrogenase etc. lost their utility due to lack of specificity and limited sensitivities. Cardiac troponin levels but negative CK-MB who were formerly diagnosed with unstable angina or minor myocardial injury is now reclassified as non–ST-segment elevation MI (NSTEMI) even in the absence of diagnostic ECG changes. CK-MB is both a sensitive and specific marker for myocardial infarction. Cardiac troponin T is a cardio-specific, highly sensitive marker for myocardial damage. Cardiac troponin I is a contractile protein exclusively present in the cardiac muscle. The absolute cardiospecificity of cTnI allows the diagnosis of myocardial infarction distinct from muscle lesions and non-cardiac surgery.

This study was carried out on the basis of literature review and the questionnaire survey on selected construction projects with 5-point Likert scale and earned value analysis to know the opinion of different parties involved. The questionnaire contained statements on practices adopted of extension of time in construction field, consequences of extension of time in the project’s cost and time and impacts of extension of time in the project’s performance through literature review. The different timing of the extension of time claim were identified for the practices of extension of time adopted in the Hupsekot Rural Municipality and the study focused the consequences of extension of time in the projects’ cost and time and the real factors for the projects time and cost overrun were also studied from Earned Value Analysis. Also, the impacts of extension of time in the project’s performance were tested through Hypothesis test method. Total of four statements from practices adopted in construction, seventeen statements from the consequences of extension of time and four statements from the impacts of extension of time in projects performance were established and administrated on twelve projects for collecting the information in Hupsekot Rural Municipality. The identified results were analyzed with Relative Importance Index (RII) and Ranking.

Banana Yoshimoto (the pen name of Mahoko Yoshimoto, born in 1964) is a Japanese writer who, like her contemporary Haruki Murakami, is distinguished by her desire to question and problematize aspects of modern Japanese society in her fiction. Banana Yoshimoto is regarded as a representative figure in contemporary Japanese fiction, foregrounding the experiences and self-questioning of a younger generation struggling to find its place in a society torn between conservatism and the contingencies of a radical, dynamic, globalized, but at the same time, consumer culture. The elusiveness of relationships, of intimacy, of love and life, the difficulty of defining and finding happiness, and the inscrutability of one’s self are some of the central themes in her writing. This paper looks at Yoshimoto’s widely acclaimed novella, Kitchen (1987), and the manner in which Mikage Sakurai, the protagonist, manoeuvers through death, loneliness and healing to arrive at a secure sense of self. This happens through the primary metaphor of the kitchen, and the gendered associations that it elicits. At the same time, Yoshimoto’s representation of this space, as well as of food in general, challenges certain stereotypes associated with these. In the process, interpersonal relationships as well as the conventional idea of family also come to be reconstituted in the novella.

Human Papilloma Virus is a group of >150 related viruses and precursor to nearly all cervical cancers and genital warts. Cervical cancer ranks 1st most frequent cancer in Nepal among 15-44 years of age women. World Health organization recommends vaccination for 9–13-year-old girls as most cost-effective public health measure to diminish the risk of HPV transmission against cervical cancer. The study aimed to assess the level of knowledge and attitude on HPV, its vaccination and risk factor of cervical cancer among adolescent girls. A descriptive cross-sectional research was conducted among 400 adolescent girls at selected schools of Dharan through Systematic Random Sampling. Data were collected using Self-administered questionnaire and analyzed using descriptive and inferential statistics at the level of significance 0.05 in SPSS version16. Majority (83.0%) of the respondents were of Middle Adolescence (14-16yrs) with mean age 15.48 years and standard deviation of ±1.031. More than half (52.8%) of respondents had adequate knowledge whereas more than half (55.5%) of respondents had negative attitude. There was no association between knowledge and attitude with socio-demographic variables. The correlation between levels of knowledge and attitude was positively significant with P value 0.01(r=0.243).The study revealed that more than half of adolescent girls had adequate knowledge where as less than half of respondents had positive attitude and there was no association between knowledge, attitude and socio-demographic variables but correlation between knowledge and attitude was found to be positive.