People must have particular personality traits and social resources, also known as health literacy, in order to access, comprehend, and use information to make decisions about their health. Patients' ability to engage in complex disease management and self-care is strongly related to their level of health literacy. It can help us stay healthy by preventing illness and effectively managing existing illnesses. People with low health literacy (LHL) may find it difficult to manage their condition and prevent illness, which may lead to increased use of healthcare services. Furthermore, LHL is associated with increased hospitalizations, increased use of emergency care, decreased use of preventative services, and a worsened ability to understand labels and health messages, a worsened state of health, higher mortality, and more expensive medical care.

In recent years, stem cell therapy has become a very promising and complex scientific research topic. In the body, stem cells have the capacity to differentiate into a wide variety of cell types. They are capable to regenerate body system. Adult stem cells and embryonic stem cells are the two primary categories of stem cells. Through cell- replacement therapies, stem cell-based therapies can give the opportunity to replace lost, damaged, or old cells in order to regenerate or repair tissues and organs. Additionally, using genetically altered stem cells as delivery systems holds enormous potential for treating inherited genetic flaws and delivering therapeutic chemicals to specifically injured tissues and organs. The ensuing integration of science and medicine made possible by more research will enable the therapeutic application of ES cell technology. In the end, such a program might present a remarkable new weapon in the fight against human sickness.

Background: Research misconduct is a global concern in biomedical science. There are no comprehensive data regarding the perception and situation of scientific misconduct among the Iranian medical faculty members. We conducted a nationwide survey to assess the research misconduct among the medical faculty members in Iran. Methods: We used the Persian version of the research misconduct questionnaire (PRMQ) on the Google Forms platform. We sent the survey link to a systematic random sample of medical faculty members in Iran (N = 4986). Descriptive analyses were performed on the individual items of the PRMQ, with frequencies and percentages for categorical and Likert-type response items, and means and standard deviation (S.D.) for continuous variables. Chi-square analysis was conducted to test hypotheses examining differences in the frequency of responses related to factors influencing misconduct. We also defined four tenure categories (TC) based on the working years of the participants as tenured faculty members. All the analyses were performed using R 3.6.0. Results: The response rate was 13.8% (692 responses). Nearly 70% of the respondents agreed that their publication output would be of higher quality if there were no publication pressure. Approximately three-quarters (N =499, 72.1%) of the respondents had been aware of some instances of research misconduct during the previous year according to their understanding of misconduct. Among the participants, 18.5% perceived the effectiveness of their associated organisation's rules for reducing research misconduct to be high or very high. Pressure for tenure was identified as the item most frequently perceived with a strong behavioural influence on engaging in research misconduct (80.2%). Conclusions: This study confirms that research misconduct needs to be actively addressed among the medical faculty members. Making policies with a focus on boosting awareness regarding the occasions of scientific misconduct and its management seems to be indispensable in the future in Iran.

Ultrasound, also known as sonography, is an imaging method that uses high-frequency sound waves to produce real-time and dynamic images of the body. Ultrasound is increasingly being used to assist Sports Medicine Physicians, Rheumatologists, Orthopedists, and Primary Care. Procedural planning prior to any procedure increases efficiency in the operative field and reduces patient discomfort. Ultrasound is commonly utilized in regenerative medicine techniques due to the ability to visualize soft tissue targets with high resolution. Ultrasound is beneficial in both diagnostic purposes and image-guidance for procedures. Understanding how to quickly optimize the ultrasound image and ergonomics for the procedure will greatly improve your procedure workflow.

Millions of patients present annually with chest pain, but only 10% to 15% have myocardial infarction. Lack of diagnostic sensitivity and specificity of clinical and conventional markers prevents or delays treatment and leads to unnecessary costly admissions. Comparative data are lacking on the new markers, yet using all of them is inappropriate and expensive. The older markers like aspartate amino-transferase, creatine kinase, lactate dehydrogenase etc. lost their utility due to lack of specificity and limited sensitivities. Cardiac troponin levels but negative CK-MB who were formerly diagnosed with unstable angina or minor myocardial injury is now reclassified as non–ST-segment elevation MI (NSTEMI) even in the absence of diagnostic ECG changes. CK-MB is both a sensitive and specific marker for myocardial infarction. Cardiac troponin T is a cardio-specific, highly sensitive marker for myocardial damage. Cardiac troponin I is a contractile protein exclusively present in the cardiac muscle. The absolute cardiospecificity of cTnI allows the diagnosis of myocardial infarction distinct from muscle lesions and non-cardiac surgery.

The present study was to evaluate the phytochemical screening and anthelmintic activity of aqueous polyherbal seed extract (APSE) against Pheretima posthuma. The seeds of Helianthus annuus, Cucurbita pepo, Linum usitatissimum, Citrullus lanatus and Cucumis melo was identified and purchased from local market of Nuzvid. APSE was prepared from the dried seeds of five different seeds using the solvent water. Initially, APSE was screened for phytochemical constituents by standard methods. Further, anthelmintic study was conducted against Pheretima posthuma, collected from local Vermicomposting Farm, Nuzvid. In the phytochemical screening, APSE showed presence of glycosides, alkaloids, flavonoids, phenols, phytosterols and tannins. In the anthelmintic study, mortality was produced in earth worm populations by APSE. The use of APSE as an anthelmintic was confirmed by using standard method against Pheretima posthuma. The results indicated that the test drug has significant anthelmintic properties. Hence, it can be concluded that the APSE can be used as a novel drug for the treatment of worm infestations.

Background: Diabetic nephropathy (DN) is a common finding in diabetic patients. Microalbuminuria is the earliest clinical evidence of DN. Early detection of microalbuminuria is very important; it allows timely interventions to prevent progression to macroalbuminuria and later end-stage renal disease (ESRD). Objectives: To determine the prevalence of microalbuminuria in diabetic patients and establish its association with traditional serum renal markers in assessment of incipient nephropathy. Methods: This cross-sectional study involved 213 participants with diabetes mellitus (DM) attending the diabetic clinic of MM Institute of MSR. Aim: We aimed to evaluate the levels of urine microalbumin, urine albumin creatinine ratio, plasma creatinine and glycosylated hemoglobin (HbA1c) among type 2 diabetic patients and assessed the correlation between microalbuminuria and plasma creatinine levels. Questionnaires were used to obtain participant data after obtaining written informed consent. Data collected included: age, sex, level of education, history of smoking and alcohol consumption, hypertension, body mass index, family history, and duration of DM. Morning spot urine samples were collected from each participant and blood drawn for analysis of other renal markers. Urine microalbumin was determined quantitatively using immunoturbidity assay (Microalbumin kit, Mindray). Results: Increase in mean level of plasma creatinine (138 μmol/L), urine microalbuminuria (310 mg/L), albumin creatinine ratio (52) and HbA1c (7.9%) was observed among type 2 DM patients. Moderate positive correlation was observed between microalbuminuria and urine albumin creatinine ratio (r = 0.643 P = 0.0008) and between urine albumin creatinine ratio and plasma creatinine (r = 0.645 P = 0.032). Conclusion: We concluded that type 2 DM patients who are at risk of developing renal impairment must be regularly monitored for microalbuminuria, urine albumin creatinine ratio, and HbA1c levels.