Background: The aim of this study was to assess the quality of life (QOL) of menopausal women in Port Harcourt, Nigeria, with a focus on understanding the sociodemographic factors and symptomatology influencing their well-being. Methods: A cross-sectional observational design utilizing semi-structured questionnaires was used. The data were collected from 320 menopausal women aged 30-60 years. Sociodemographic characteristics, menstrual history, menopausal symptoms, and QOL were evaluated using validated scales and statistical analyses. Results: Significant findings included a prevalence of hot flashes (68.3%) and depressive moods (73.1%) among the participants. Sociodemographic factors such as age (p=0.023), marital status (p=0.004), education (p=0.017), and religion (p=0.001) were significantly associated with QOL domains. Psychological symptoms, including anxiety and intrusive thoughts, significantly impacted work efficiency (p=0.014), family relationships (p=0.035), and home responsibilities (p=0.002). Overall, 70.0% of participants reported poor QOL, highlighting the substantial burden of menopausal symptoms on daily functioning and social interactions. Conclusion: Improving menopausal women's quality of life in Port Harcourt requires accessible education, tailored healthcare, and supportive policies. Integrating menopause awareness into primary healthcare and offering psychological support are crucial for symptom management and overall well-being. Empowering women with targeted resources and supportive environments will effectively enhance their quality of life during this life transition.

The Buschke-Lowestein tumor, also known as giant condyloma acuminatum, is a neoplasm affecting the anogenital region. It is caused by human papillomavirus (HPV). The lesion is characteristically slow-growing and warts-like, with a propensity for occurrence in the anogenital region. The preferred management approach is surgical resection. However, there is ongoing debate regarding the optimal use of radiotherapy, systemic chemotherapy, and topical agents.

When we discuss homoeopathy, invariably the Bowel Nosodes group drugs are an integral part of homoeopathic materia medica. All these are leading anti-inflammatory & immune-boosting dealing drugs of homoeopathic materia medica, the nosodes from the bowel are the drugs that the article discusses. Nosodes are those drugs in homoeopathy which are prepared from the disease related products or organisms. This means these are the gut bacteria from which medicines are prepared as per the homoeopathic pharmacopeia. The article looks into the role of one such bowel nosode from the Oscillibacter species. The article looks into the scientific aspects of these dealing drugs to deal with hypercholesterolemia. The future use of the drugs in the Non-Communicable Disease (NCD) like high cholesterol levels on a large scale will only benefit the masses. The drugs are cost effective, therapeutically active with no side effects & these properties only augur well for large scale application of homoeopathy on NCDs. The use of these drugs is authenticated by the scientific research of the gut bacteria on reducing cholesterol. For the benefit of the masses, the homoeopathic perspective, use & a treatment protocol is described in this article. The protocol is based on the bowel nosodes that can help in reducing cholesterol. The authority books of homoeopathic materia medica & the encyclopedia of homoeopathy are referred in the article.

Benign prostatic hyperplasia (BPH) is also called enlargement of the prostate. It is an old age disease. it is found in males. It is mostly found above the age of 50. Due to the increase in the size of the prostate, there found various symptoms like difficulty in micturition, and painful urination. Nocturia, lower abdominal pain, incontinence, intermittent. The main cause of Benign prostatic hyperplasia is testosterone excess, which converts into Dihydrotestosterone (DHT) by 5 alpha reductases enzyme. Dihydrotestosterone is an active form of testosterone. Which binds with the glandular tissue of the prostate gland and is responsible for increasing the size of the prostate gland. The homeopathic mother tincture is very effective in treating Benign prostatic hyperplasia. Different types of homeopathic literature present about effects of homeopathic medicine. This article tries to present information for homeopathic physicians and homeopathic practitioners to treat and manage cases of Benign prostatic hyperplasia. This article also helps to reduce complications and severity of symptoms of Benign prostatic hyperplasia. Homeopathic Mother Tincture is effective in treating prostate and helps in avoiding surgery. This search strategy for this review article included all clinical trials, observational studies, and reviews published in the past years. Google, Homeopathic Materia Medica, websites and books, and Wikipedia were also searched to enrich the review. This review has attempted to present this information.

Objective: To gather expert opinion regarding prescription practices and management strategies for neuropathy and vitamin B12 deficiency with a special focus on methylcobalamin among clinicians in Indian settings. Methodology: This cross-sectional study utilized a 24-item, multiple-response questionnaire to gather expert opinion from specialists in managing neuropathy and vitamin B12 deficiency. The survey encompassed questions about current prescription practices, clinical observations, preferences, and experiences related to managing neuropathy and vitamin B12 deficiency in patients in routine settings. Results: The survey included 81 experts, with more than half (62.96%) of clinicians identifying diabetes as a significant confounding factor for neuropathy in patients. As indicated by 46% and 44% of the clinicians, an appropriate diet for nutrition and maintaining glycemic levels helps to overcome the progression of neuropathy. A significant proportion of experts (60.49%) reported that 26% to 50% of patients with neuropathy have vitamin B12 deficiency. Additionally, 73% of clinicians noted that diabetes mellitus is a common co-morbid condition with vitamin B12 deficiency. In patients with neuropathy complications, 74% of clinicians preferred benfotiamine alongside vitamin B12. As stated by 44% of clinicians, besides those patients with neuropathy, elderly patients are also recommended with methylcobalamin 1500 mcg. About 43% of clinicians suggested a 12-week duration for prescribing a combination of benfotiamine and methylcobalamin for patients with neuropathy. Additionally, more than half (54.32%) of clinicians favored prescribing a combination of methylcobalamin 1500 mcg, pregabalin 75 mg, and nortriptyline 10 mg tablets to patients with chronic neuropathic pain. Conclusion: The survey highlights diabetes as a significant factor in neuropathy management, emphasizing the importance of nutrition and glycemic control. A high prevalence of vitamin B12 deficiency is noted among diabetic patients with neuropathy, leading to recommendations for benfotiamine and methylcobalamin supplementation. Additionally, the use of combination therapy for chronic neuropathic pain demonstrates a comprehensive approach to improving patient outcomes.

The Objective of this research to convert sulfamethoxazole to nano-sulfamethoxazole by Sol-gel method and prepare a pharmaceutical formulation of sulfamethaxazole, prepared at a concentration of 0.25% and in the form of a spray to treat fungal and bacterial infections resulting from wounds of skin, its good for heath. The nano particles characterized by powder X-ray Diffraction (PXRD), atomic force microscope (AFM), Scanning electron microscopy (SEM). The results showed successful that nano sphere sulfamethoxazole and it size between (37-55) nm, all these tests showed different type of nanostructures such as nanotubes and nanoparticles, other biological test MIC & MBC show superior biological activity. The stability of the prepared formula was studied for 6 months under temperature conditions (30, 40) degrees Celsius and relative humidity (70, 75) controlled, which showed the stability and stability of the composition. An experiment was also conducted on laboratory animals (mice) by making a wound in them and treating with the prepared formula with a comparison with the normal non-nanostructure.

This study was conducted on patients with diabetes, in Samarra General Hospital. In this study, 50 blood samples were collected, 30 of which were taken from patients with diabetes, 20 of which were from non-diabetic people of both sexes, for ages (18_65) and for the period December 5, 2022 to the period is 1 February 2023. Blood was separated to obtain serum for biochemical analyses, and whole blood was sampled for CBC testing. The sugar test was conducted to ensure the presence of diabetes first, and the study confirmed that there was a significant increase in the patients compared to the control group, where the FBG test was conducted, and we note that there is a significant increase in the FBG test for patients with diabetes. A uric acid test was conducted, and the results showed a significant increase in patients compared to the control group, as the results of the analysis indicated that patients with diabetes appeared to have a significant increase in uric acid levels. The urea and creatinine test did not find a significant difference compared to the control group. As for the cbc test, the results for rbc, wbc, plt, hb, pcv showed no significant difference.