The concept of targeted drug delivery is designed to attempt to concentrate the drug in the tissues of interest while reducing the relative concentration of the drug in the remaining tissues. As a result, the drug is localized to the targeted site. Therefore, the surrounding tissues are not affected by the drug. Therefore, carrier technology provides an intelligent approach to drug delivery by coupling drugs to carrier particles such as microspheres, nanoparticles, liposomes, niosomes, etc., modulating the release and absorption characteristics drug revenue. Microspheres are typically free-flowing powders made of proteins or synthetic polymers that are biodegradable in nature and ideally have a particle size of less than 200 μm. It is a reliable way to deliver drugs to the target site with specificity, if altered, and to maintain the desired concentration at the site of interest without side effects. Microspheres have received a great deal of attention not only for sustained release but also for targeting anti-cancer drugs to tumors. In the future, by combining various strategies, microspheres will occupy a central place in the delivery of new drugs, especially in the classification of diseased cells, diagnostics, genes and genetic material, safe, targeted and effective in vivo delivery and supplements in miniature versions of diseased organs and tissues in the body.

Optimizing patient local and systemic circumstances, as well as creating an optimum wound healing environment, are essential components of successful wound care. Many products have been developed to impact the wound environment in order to offer a pathogen-free, protected, and moist environment in which to heal. In the wound healing cascade, newer items are being employed to replace or supplement various substrates. The latest applications of silver in microbial prophylaxis and treatment, including issues involving resistance and side effects, the latest uses of negative pressure wound devices, advanced dressings and skin substitutes, biologic wound products, including growth factor applications, and hyperbaric oxygen as an adjunct in wound healing are all covered in this review of the current state of the art in wound-healing products. With so many options, it's easy to get overwhelmed.

Abstract: A life-threatening fungal infection has rise that further exacerbates the terrible circumstances of the COVID-19 pandemic in India and nearby South Asian countries. The fungal infection more commonly being referred to as black fungus (Mucormycosis) infection due to its blackening effect on the skin, is on the rise amongst patients affected with or recovering from COVID-19. India has already reported the highest occurrence of mucormycosis in the world. As of June 28, 2021, India has reported 40,845 cases of black fungus, with the highest reported cases in Gujarat and Maharashtra. Also, the country reported 3,129 related deaths till June 28, 2021.

Hydrogels are crosslinked polymer networks that absorb substantial amounts of aqueous solutions. Hydrogels can be divided into two categories based on the chemical or physical nature of the crosslink junctions. Chemically crosslinked networks have permanent junctions, while physical networks have transient junctions that arise from either polymer chain entanglements or physical interactions such as ionic interactions, hydrogen bonds, or hydrophobic interactions .Hydrogels, the swellable polymeric materials, have been widely investigated as the carrier for drug delivery systems. These biomaterials have gained attention owing to their peculiar characteristics like swelling in aqueous medium, pH and temperature sensitivity or sensitivity towards other stimuli. Hydrogels being biocompatible materials have been recognized to function as drug protectors, especially for peptides and proteins, from in vivo environment. Also these swollen polymers are helpful as targetable carriers for bioactive drugs with tissue specificity. This article presents an overview to the advances in hydrogel based drug delivery that have become the interest of most researchers.

Letter to the editor

Worldwide, one in eight deaths is due to cancer. Projections based on the GLOBOCAN 2012 estimates predict a substantive increase new cancer cases per year by 2035 in developing countries if preventive measures are not widely applied. According to the World Health Organization (WHO), millions of lives could be saved each year if countries made use of existing knowledge and the best cost-effective methods to prevent and treat cancer. Therefore, the aim of this study is to estimate a provisional budget against cancer in low and middle incomes countries, according the GNI-PPP, the cancer incidence and the number of population. Economically country classification is determining with the Gross national income (GNI), per capita, Purchasing power parity (PPP), according the administrations of the International Monetary Fund (IMF), the World Bank (WB) and the Central Intelligence Agency (CIA). Cancer incidence data presented are based on the most recent data available at IARC. However, population compares estimates from the US Bureau of the Census. The provisional budget is establishing among the guidelines developed by WHO for regional and national cancer control programs according to national economic development. Provisional budget against cancer is estimated to 179,449.419 (thousands of U.S $) for a population of 27,499,924 persons in Ghana.

Worldwide, one in eight deaths is due to cancer. Projections based on the GLOBOCAN 2012 estimates predict a substantive increase new cancer cases per year by 2035 in developing countries if preventive measures are not widely applied. According to the World Health Organization (WHO), millions of lives could be saved each year if countries made use of existing knowledge and the best cost-effective methods to prevent and treat cancer. Therefore, the aim of this study is to estimate a provisional budget against cancer in low and middle incomes countries, according the GNI-PPP, the cancer incidence and the number of population. Economically country classification is determining with the Gross national income (GNI), per capita, Purchasing power parity (PPP), according the administrations of the International Monetary Fund (IMF), the World Bank (WB) and the Central Intelligence Agency (CIA). Cancer incidence data presented are based on the most recent data available at IARC. However, population compares estimates from the US Bureau of the Census. The provisional budget is establishing among the guidelines developed by WHO for regional and national cancer control programs according to national economic development. Provisional budget against cancer is estimated to 256,568.421 (thousands of U.S $) for a population of 4,926,330 persons in Georgia.