Just look at regular intake of two fruits ie; apple and apricot may help to escape patients from sufferings related to hyperlipidemia. These two fruits have had been researched by scientist for treatment of hyperlipidemia by decreasing low density lipoprotein cholesterol (LDL-C) and increasing high density lipoprotein cholesterol (HDL-C). It was placebo based research work conducted at General Hospital Lahore from January to April 2022. 100 already diagnosed patients of primary/secondary hyperlipidemia were enrolled in research study with (written/explained and approved) consent. Inclusion criteria was their age (20-70 years), gender (male and female) and patients not on any hypolipidemic allopathic medicines. Exclusion criteria was smokers, alcoholic addictives, and patients of thyroid, liver, lung, and severe heart related diseases. Grouping: They were divided in four equal groups including 25 patients in each group. Group-one was on apple half kg per day for the period of three months. Group-two was on apricot half kg per day for the period of three months. Group-three was on apple ½ kg plus apricot ½ kg for the period of three months. Group-four was placebo group and they were advised to take any fruit except these two fruits ie; apple and apricot. Method: Their name/age/gender/occupation/address/cell number was kept in separate folder for research record. Their base line lipid profile was determined at pathology/biochemistry laboratory of the hospital. Fortnightly visit was advised to them. After three months therapy their lipid profile was re-determined. Mean values of their LDL-C and HDL-C ± SEM was analyzed biostatistically by applying paired t-test. P-values >0.05 was regarded as non-significant, p-values <0.01 and <0.001 were regarded as significant and highly significant changes in tested parameters respectively. Results: After three months therapy it was observed that apple reduced LDL-cholesterol 23.77 mg/dl and increased HDL-cholesterol 3.3 mg/dl. Apricot reduced LDL-cholesterol 7.5 mg/dl and increased HDL-cholesterol 5.3 mg/dl. Combination of both fruits decreased LDL-cholesterol 16.1 mg/dl and increased HDL-cholesterol 6.6 mg/dl in three months therapy. Conclusion: It was concluded from results of this research work that apple and apricot given separately or in combination, have remarkable effect on LDL-C and HDL-C in patients suffering from primary/secondary hyperlipidemia.

Objective: The main objectives of the study are preliminary phytochemical screening, antioxidant activity and in vitro thrombolytic activity evaluation of extract Phlogacanthus thyrsiflorus. Methods: Preliminary phytochemical analysis was done by using standard methods. Human blood clot lysis was used to evaluate the thrombolytic activities. The antioxidant activity is evaluated by free radical scavenging activity of DPPH (1,1-diphenyl-2-picrylhydrazyl) method and total phenolic content. Results: Preliminary phytochemical screening revealed the presence of various bioactive components like Tannin, Saponins, Phenol and Flavonoids. In thrombolytic assay, a significant clot lysis was observed plant extract compared to the negative control. The plant could be beneficial in synthetic drug formulation by virtue of the presence of antioxidant activity. The crude extract of plant were found to have Antioxidant activity with the concentration of 20 µg/ml, 40 µg/ml, 60 µg/ml, 80 µg/ml, 100 µg/ml respectively compared to control and standard. In DPPH scavenging assay, IC50 values of extract and ascorbic acid were found to be 31.87 µg/ml and 52.04 µg/ml respectively. Total phenol content was 10.5 mg. Conclusion: In conclusion, with this study it could be concluded that the phytochemical, antioxidant assay and thrombolytic activity of methanol extract Phlogacanthus thyrsiflorus would give valuable information for further characterization and exploitation of this important medicinal plant.

Premenstrual Syndrome (PMS) is a common phenomenon experienced by many women in the days leading up to their menstrual cycle. The physical and emotional symptoms can range from mild discomfort to severe disruptions in daily life. While conventional treatments exist, an increasing number of individuals are turning to herbal approaches to find relief from PMS symptoms such as Chaste Tree (Vitex agnus-castus), Evening Primrose Oil (Oenothera biennis), Dong Quai (Angelica sinensis), Ginger (Zingiber officinale), In addition to herbal remedies, lifestyle and dietary adjustments play a crucial role in managing PMS. A diet rich in whole foods, particularly fruits, vegetables, and whole grains, can contribute to overall well-being. Regular exercise has been shown to reduce PMS symptoms by promoting circulation and releasing endorphins, the body's natural mood elevators. The herbal approach to managing PMS offers a natural and holistic alternative for women seeking relief from the challenges of premenstrual syndrome. While individual responses to herbal remedies may vary, many women find comfort and support in the wisdom of nature.