Rota virus is the second causes of diarrhea among childrenIn Sudan [2]. The current study was conduct to detect rotavirus gastroenteritis among vaccinated children Methodolgy: A total of59 diarrheal samples was collected from children with acute diarrhea admittedto Mohammed AL Amin Hamid paediatric Hospital throw period from October to November 2019, ELISA was dine to detect Rota virus antigen. Result: Out of 59 samples 84.7% was vaccinated were 15.3% was unvaccinated.in total of 50 vaccinated children 30% is re-infected with rota virus with acute to chronic illness and show positive antigen with ELISA. Conclusions: vaccinated children is infected with rota virus and symptoms is occurs samples for virus antigen was record positive result in ELISA this may related to other genotype or serotype or mutation.

This study aimed to evaluate the antifungal activity of Cinnamon extract on Candida species isolated from 100 diabetic patients suffering from urinary tract infection between May to August 2018. Twenty-five Candida species were isolated, different Candida species were isolated then identified biochemically, in vitro sensitivity testing using well diffusion technique against Cinnamon extract was done. The cinnamon extract showed good antifungal activity against Candida species. The largest zone of inhibition against Candida tropicalis was (25 mm) and the least zone of inhibition was against Candida kefyr was (10 mm). The results of antimicrobial activity of crude extract were compared with the positive control (Clotrimazole) for evaluating their relative percentage inhibition and statistical significance the aqueous extract exhibited maximum relative percentage inhibition against Candida kefyr (89%) and minimum relative percentage inhibition against Candida glabrata was (12.3%). The p. values (0.018) are statistically significant.