Purpose: To observe the blood picture of patients with COVID 19 infections and to formulate future guidelines for management. Methods: This cross-sectional descriptive study was carried out among patients with COVID 19 infections who were admitted to one of the Covid-dedicated hospitals in Bangladesh from March-2020 to May-2020. Results: A total of 92 patients were included in this study. 53.3% were male and 46.7% were female. Most of the patient’s haemoglobin percentage was found below normal (53.3%), however, the total count of RBC, WBC and Platelet was found within the normal limits in most of the cases (64.1%,80.4% and 87% cases respectively). 75% of patients had high ESR levels. 50% of cases showed Neutrophilia and Lymphocytopenia in 43.5% cases. Although some cases show changes in Monocyte, Eosinophil and Basophil count they were not significant in number. Conclusions: A significant number of patient’s neutrophilia and lymphocytopenia. Blood parameter is an important tool for managing the COVID-19 patients. With or without co-morbidities maintaining normal blood levels is essential in COVID-19 patient management.

Purpose: Diabetes can increase oxidative stress in various tissues of the body, and the progress of this process is associated with intensification of the complications of diabetes. The current study purposed to evaluate the protective effect of Pinus gerardiana (PG) seed on oxidative stress induced by diabetes in the liver and serum of streptozotocin (STZ)- induced diabetic rats. Materials and Methods: This interventional study was performed on 36 male Wistar rats. The rats were randomly divided into 6 groups (healthy controls, healthy treated with 3% and 6% (PG), diabetic control, diabetic treated with 3% and 6% (PG) doses). After 6 weeks of intervention, weight, glucose, and oxidative stress parameters in serum and liver including total antioxidant capacity, malondialdehyde, total thiol and superoxide dismutase activity were measured. Data analysis was done by statistical software version 16 and Tukey’s one-way ANOVA tests. Results: Diabetic rats showed significantly higher malondialdehyde and fasting glucose levels (12±1.2 mmol/L) and significant reductions in fasting insulin serum, weight (−37%), and activity of superoxide dismutase enzymes, total thiol groups, and total antioxidant capacity of serum and liver (about +49% in liver and +16% in serum) (p < 0.001) compared with the healthy groups. Oral administration of PG nuts to diabetic rats caused a significant reduction in malondialdehyde and fasting glucose levels (−43%) and weight loss (+15%), and a significant increase in activity of superoxide dismutase enzymes, total thiol groups, and total antioxidant capacity of serum and liver (p < 0.001). Conclusion: The present study concluded that PG can decrease fasting blood glucose, improve insulin resistance, reduce weight loss, and improve oxidative stress indices in the serum and liver of STZ-induced diabetic rats. It is a potential therapeutic food supplement for the treatment and prevention of hyperglycemia and high oxidative stress of diabetes.