The present work deals with the qualitative and quantitative analyses and the assessment of the antioxidant properties of the extracts of the propolis of Boyo. It appears from this study that the polarity of the solvent used and the yield obtained are inversely proportional. We see here that hexane, apolar solvent presents an extraction yield of 52.08% while methanol, the most polar solvent presents only a yield of 5.21%. The qualitative analysis shows that these extracts contain enough compounds of natural substances and rich in polyphenols in particular flavonoids. The quantification of polyphenols is 0.68 ± 0.09 g EAG/100 g MB for the hexane extract, 2.64 ± 0.43 g EAG/100 g MB for the ethyl acetate extract and 12.64 ± 0.23 g EAG/100 g MB for the methanol extract, then that of flavonoids is 0.21 ± 0.05 g QE/100 g MB for the hexane extract, 0.92 ± 0.03 g QE/100 g MB for the ethyl acetate extract and 2.02 ± 0.02 g QE/100 g MB for the methanol extract. The study of antioxidant activities and the quantification of phenolic compounds of these same extracts showed interesting properties that propolis extracts possess.