This study investigated the detrimental effects of Xenical, both independently and in conjunction with cinnamon, on the histological alterations in renal tissue of obese male rabbits. The study evaluated the preventive properties of cinnamon extract by analyzing its ameliorative impact on the pathological alterations in renal tissue induced by the drug Xenical. Twenty mature male rabbits were categorized into two groups. Rabbits were administered chloroform anesthetic to induce unconsciousness, after which they were euthanized and dissected to obtain kidneys for pathological examination. Histological analysis of the kidney portion from the control group revealed the usual histological architecture of the renal cortex, characterized by prominent glomeruli and orderly renal tubules. The histological examination of kidney sections from the high-fat diet group was stained with hematoxylin and eosin, revealing an abnormal renal cortex, significant infiltration of inflammatory cells into the interstitial space, considerable glomerular atrophy, tubular necrosis, and marked alterations in the glomeruli, characterized by interstitial inflammation surrounding the glomeruli. Histological analysis of kidney sections from the high-fat diet and Xenical group, stained with hematoxylin and eosin, revealed mild histological improvements in cortical tissue, glomerular atrophy, dilation of Bowman’s capsule, infiltration of interstitial inflammatory cells, and significant degeneration of tubular epithelium. Histological examination of kidney sections from the high-fat diet and cinnamon group, stained with hematoxylin and eosin, revealed significant histological improvements in renal cortical tissue, including normal glomeruli, normal tubules, slight infiltration of interstitial inflammatory cells, and mild degeneration. Histological examination of kidney sections from the high-fat diet and Cinnamon with Xenical group, stained with hematoxylin and eosin, revealed several histological alterations in renal tissue, including normal glomeruli with minor atrophy, normal tubules, slight infiltration of interstitial inflammatory cells, and pronounced congestion accompanied by mild degeneration and congestion.

This laboratory study was conducted to test the effect of extracts of plants, leaves and sepals of hibiscus plant Hibiscus sabdariffa, leaves of Pinus sp and leaves of Eucalyptus Camaldulenis on the mortality of adults southern cowpea weevil Callosobruchus maculates (Fab) with six concentrations (1000, 2000, 5000, 7000, 9000, 10000) ppm / adult and using the solvent (ethanol and distilled water) and the results were noted after 24 and 48 hours of treatment. The study also tested the effect repellency and attraction Extract ethanol & aqueous plants under study against insect adults and after 15 and 30 minutes of treatment. The results showed that there were influential for each plant extracts used in the study of death adults. Results of the statistical analysis showed that there were significant differences in the toxicity of plant extracts depending on the type of plant and extract concentration, where it was noted that mortality rates increased in direct correlation with the increase in concentration and duration of exposure in each treatment. So, the results showed a various effect in the proportions of attraction and repellency depending on the type of plant extract concentration and time against adults. The results showed that the alcoholic extracts of plants under study super-passed significantly the aqueous extracts on death of adults. And eucalyptus leaves extract in solvents (ethanol and distilled water) outweigh all plant extracts used in the study in their impact on the insect. While the plant extract Hibiscus sepals is the least influential in the insect.