Background: Anemia during pregnancy is commonly caused by iron deficiency anemia. It can cause severe consequences for both the fetus and the mother. This study aims to compare the safety and efficacy of IV iron sucrose and IV iron ferric carboxy maltose in pregnant patients with anemia. Material and Methods: This is a prospective observational study; all women treated with iron sucrose & FCM for anemia during pregnancy between January 2021 to June 2021 at Department of Obstetrics and Gynaecology, Ganesh Hospital, Ghaziabad. Total 36 women were selected. Each study group consisted of 18 women receiving FCM which was group A and 19 in group B receiving Injection Iron Sucrose between 30 and 36 weeks of pregnancy. Treatment effectiveness was assessed by repeat Hemoglobin and Serum Ferritin level measurement after 4 weeks of completion of therapy. Safety was assessed by analysis of adverse drug reactions during infusion and 2 hours after infusion. Results: Intravenous ferric carboxymaltose infusion significantly increased Hemoglobin values compared to Intravenous ferrous sucrose. None of the women developed serious adverse reaction in FCM group whereas 3 drug reactions were noted in patients treated with Iron sucrose. Conclusion: Ferric carboxymaltose can be used safely in Iron defciency anemia complicatinin pregnancy and has shown to have better results.