South Asian Research Journal of Applied Medical Sciences (SARJAMS)
Volume-7 | Issue-04
Case Report
Bullous Pemphigoid Simulating Pseudoporphyria Case Report
Rolon-Aguilera Sharon Danai, Mendoza-Vázquez Víctor Cristóbal, Chávez-Chavira Grecia, Camacho-Cedeño Laura Patricia, Ramírez-Hernández Vianca Andrea, Conde Vázquez Eliezer
Published : July 21, 2025
Abstract
Bullous pemphigoid is an autoimmune disease that predominantly affects older adults. It is characterized by autoantibodies against the hemidesmosome proteins BP180 and/or BP230, and elevated levels of serum IgE, eosinophils, and chemokines in skin lesions. It typically presents pruritic, eczematous, excoriated, urticarial-like lesions; the treatments include high-potency topical corticosteroids, oral prednisone, immunosuppressants, doxycycline, dapsone, B-cell depletion therapy, intravenous immunoglobulin, as well as biologic drugs. In this report, we present the case of 63- year-old patient with a previous diagnostic of systemic arterial hypertension who developed multiple tense vesicle and bullas at photo exposed skin areas.