Pyoderma gangrenosum was first described in 1908 and is a rare neutrophilic disease not associated with infection. It is characterized by the appearance of painful skin ulcers with undermined and irregular edges, usually purplish in color and with peripheral erythema. It most commonly affects the lower extremities, although it can occur in other locations, including the genital, perineal, and perianal regions. (1) There is a relationship between this condition and inflammatory bowel disease, as well as other autoimmune diseases and even neoplasms. It is my understanding that the physician is able to understand and explain to family members the estimated time of healing and the importance of the phenomenon of pathergy in the disease. This is possible because knowing the evolution of the lesions allows the physician to understand the phenomenon of pathergy. We present the case of a patient with lesions that appear to be pyoderma gangrenosum on the head, showing how they have evolved until resolution.