South Asian Research Journal of Medical Sciences (SARJMS)
Volume-7 | Issue-04
Case Report
Localized Bullous Pemphigoid Associated with Chronic Venous Stasis: A Case Report
Uriarte-Ruiz Karen, Aguilar-García Alejandra, Sánchez-Martínez Sandy Mildreth, Lopez-Jiménez Fanny Carolina, Perez-Campos Alexandra Emma, Rosas-Sandoval Cynthia Paola
Published : July 10, 2025
Abstract
Bullous pemphigoid (BP) represents one of the most prevalent forms of bullous diseases. Nevertheless, its localized variant, known as Localized Bullous Pemphigoid (LBP), is relatively uncommon, comprising only 2.5% of all BP cases. LBP is typically associated with trauma and may manifest on any wound or surgical site. Although chronic venous stasis has not been well-documented as a predisposing factor. We present the case of an 80-year-old man who exhibited blistering lesions localized to his left lower limb. He had a history of chronic venous insufficiency (CIV) on both legs, with no improvement after surgery. Clinical-pathology correlation concluded with the diagnosis of LBP. Treatment with clobetasol topical ointment and compression therapy led to complete remission of the skin lesions after one month. This report underscores chronic venous stasis as a contributing trigger for LBP.